Endocrine Abstracts

Background: Thyroglobulin (Tg) is a promising biomarker for monitoring iodine nutrition in children and pregnant women. The determination of Tg in dried blood spots (DBS) offers many logistical advantages, simplifying the collection, transport, and storage of samples. The present study aimed to validate an ELISA assay for Tg determination in newborns.Methods: Tg-DBS samples were measured in 196 newborns born from healthy pregnant women. The different cri...

Background: Thyroglobulin (Tg) is a promising index of iodine status in pregnant women and children. The present study aimed to test a new strategy facilitating the monitoring of iodine status using Tg dried blood spot (DBS) in newborns.Methods: Pregnant women were recruited in the third trimester of pregnancy at the Erasme Hospital in Brussels, Belgium. Thyroglobuline concentrations and urine iodine concentrations (UIC) were determined in pregnant women...